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The Chemotype System

How to read the 6-digit code and classify the expected effect profile along with variety, origin, and batch analysis.

Brief & Concise

The Chemotype is a 6-digit code that lists the six main kavalactones in descending order of their concentration. It does not contain exact percentage values but provides useful guidance on which kavalactones can particularly shape the profile.

The Chemotype is a 6-digit code that lists the six main kavalactones in descending order of their concentration. It does not contain exact percentage values but provides useful guidance on which kavalactones can particularly shape the profile.

The system established by Vincent Lebot is an important tool for classification and quality control. For classification as Noble or Tudei and for a reliable expectation of effects, variety identity, plant parts, origin, processing, batch analysis, and experience are also considered.

The Numbering of Kavalactones

Each of the six main kavalactones is assigned a digit. This assignment is historically based and follows the order of their discovery or chromatographic elution:

DigitKavalactoneAbbreviationMain Effect
1DesmethoxyyangoninDMYFocus, Motivation, Social Openness
2DihydrokavainDHKMuscle Relaxation, Analgesia
3YangoninYMood Enhancement, Light Euphoria; CB1 Affinity in vitro
4KavainKAnxiolytic, "Heady" Effect
5DihydromethysticinDHMDeep, body-focused, and often longer-lasting relaxation
6MethysticinMSedating, Neuroprotective

Reading a Chemotype

The chemotype is written as a 6-digit number, with each position indicating the relative concentration:

1st Place
4
Highest Conc.
2nd Place
2
Second Highest
3rd Place
6
Third Highest
4th Place
5
Fourth Highest
5th Place
3
Fifth Highest
6th Place
1
Lowest

Examples & Interpretation

426531

Kavain-Dominated Example Profile

Kavain is in first place, Dihydrokavain in second; followed by Methysticin and Dihydromethysticin. In practice, this ranking often corresponds to clear, focused relaxation with noticeable physical calm.

246531

DHK-Dominated Example Profile

Dihydrokavain > Kavain > Methysticin > Dihydromethysticin > Yangonin > Desmethoxyyangonin

526431

DHM-Dominated Example Profile

DHM (5) in first place indicates a significantly heavier, body-focused, and potentially longer-lasting profile. Such profiles are often described as associated with fatigue, nausea, or a lingering feeling the next day.

256431

DHK/DHM-Dominated Example Profile

DHK (2) and DHM (5) at the top indicate a strongly body-related and rather heavy effect. Whether the sample is Noble or Tudei must be clarified through variety identity and quality data.

Noble Kava vs. Tudei Kava

The distinction between Noble Kava (Noble Kava) and Tudei Kava (Two-Day Kava) is important for Kava quality. Tudei profiles are traditionally described as heavier and longer-lasting; however, safe classification requires variety identity and quality data, not just a sequence of digits.

CriterionNoble KavaTudei Kava
Chemotype StartOften 4- or 2-dominated; chemotype alone is not proofOften higher DHM content; variety and quality testing required
Onset of EffectsOften perceived faster in reportsSometimes perceived delayed in reports
Duration of EffectsOften described as moderate and well-fadingOften described as significantly longer and lingering
Character of EffectsClear, relaxed, socialDull, sedating, groggy
Side EffectsUsually well-tolerated with appropriate quality and preparationOften associated with nausea, headaches, or lingering feelings
Export ApprovalYes (regulated)No (prohibited in Vanuatu)
Example VarietiesBorogu, Melo Melo, Kelai, Bir KarIsa, Palimanu, Wildkava

Indicators of Tudei-like Profiles

The chemotype can provide clues but does not replace variety and batch testing:

Indicators for a More Accurate Examination

  • 5 in position 1 or 2
  • 5 before 4 in the chemotype
  • Very high total DHM content (>15%)

Common Features of Esteemed Noble Profiles

  • Documented Noble variety identity
  • Suitable underground plant parts and traceable origin
  • Batch analysis or COA with plausible quality values

Effect Profiles by Chemotype

In practice and reports, Kava profiles are often described as Heady, Heavy, or Balanced. The chemotype supports this classification but does not solely determine it:

🧠

Heady Kavas

Not solely derivable from an initial digit

Heady profiles are described as providing clear, mental relaxation, focus, talkativeness, and a pleasant mood enhancement. A high relative Kavain content often fits this impression.

Ideal for:

  • Social occasions and conversations
  • Creative work
  • During the day or early evening
  • Beginners (milder effect)

Practice: The specific variety and batch should be described sensorily and analytically.

💪

Heavy Kavas

Not solely derivable from an initial digit

Heavy profiles are described with pronounced physical calm, noticeable muscle relaxation, and stronger evening or sleep proximity. DHK, Methysticin, and DHM can contribute to this overall impression.

Ideal for:

  • Evening relaxation
  • Stress relief and muscle relaxation
  • Preparing for sleep
  • Experienced Kava drinkers

Practice: The specific variety and batch should be described sensorily and analytically.

⚖️

Balanced Kavas

Not solely derivable from a single code

Balanced profiles combine mental clarity and friendly mood with noticeable physical relaxation. They are often experienced as versatile and suitable for everyday use.

Ideal for:

  • Daily use
  • Meditation and mindfulness
  • Versatile use (day or evening)
  • All experience levels

Practice: The specific variety and batch should be described sensorily and analytically.

Chemotype & Quality Control

The chemotype is an important instrument for quality control in international Kava trade. It becomes meaningful when combined with variety identity, plant parts, origin, processing, and batch-related laboratory values.

Tip for Consumers: Reputable Kava vendors provide the chemotype of their products or can disclose it upon request. If a vendor cannot provide chemotype information, caution is advised.

Proceed to the next category:

Varieties & Strains

Over 80 documented Kava varieties and their properties

Based on studies by

Vincent Lebot

CIRAD, French Agricultural Research Centre for International Development

View profile

With contributions from

This wiki is a curated resource that synthesizes research from peer-reviewed studies and expert researchers. It is not written by the researchers listed above, but rather based on their published work.

Scientific Sources

The information on this page is based on the following scientific studies and publications:

Measuring the Chemical and Cytotoxic Variability of Commercially Available Kava (Piper methysticum G. Forster)

Unknown (Unknown) – Unknown

View study

Kava: The Pacific Elixir - The Definitive Guide to Its Ethnobotany, History, and Chemistry

Vincent Lebot, Mark Merlin, Lamont Lindstrom (1997) – Yale University Press

View study